MULTIPARTICULATES OF PREFERABLY AN OPIOID, AND MET

专利名称：MULTIPARTICULATES OF PREFERABLY AN

OPIOID, AND METHOD OF

MANUFACTURING USING EXTRUSION

发明人：HAYES, Geoffrey Gerard, Napp

Pharmaceuticals,MARTINELLI, Vincenzo,Napp Pharmaceuticals

Research,MOHAMMAD, Hassan, NappPharmaceuticals Research,TAMBER, Harjit,Napp Pharmaceuticals Research,WALDEN,Malcolm, Napp PharmaceuticalsResearch,WHITELOCK, Steve, NappPharmaceuticals Research

申请号：EP05781628.2申请日：20050831公开号：EP1809249A2公开日：20070725

摘要：Extrusion of a mix containing a pharmaceutically active agent can be achievedusing a plasticising excipient in an amount sufficient to act as plasticiser and also act aslubricant, thereby avoiding the need for inclusion of a lubricant. The invention providesmultiparticulates with controlled release properties, substantially free of lubricant.

申请人：Euroceltique S.A.

地址：122 Boulevard de la Petrusse L-2330 Luxembourg LU

国籍：LU

代理机构：Ruffles, Graham Keith

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