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STRAINS AND METHODS FOR PLASMID MAINTENANCE

来源:知库网
专利内容由知识产权出版社提供

专利名称:STRAINS AND METHODS FOR PLASMID

MAINTENANCE

发明人:Paul Campbell,Ryan W. Black,Stephanie

Doneske,Mai Li,Daniel J. Monticello

申请号:US14601639申请日:20150121

公开号:US20150232805A1公开日:20150820

摘要:The present invention provides a host microorganism with a deletion, disruptionor mutation in one or more enzymes of a glycerol dissimilation pathway and a plasmidwithout an antibiotic resistance gene but carrying one or more genes encoding enzymesinvolved in glycerol dissimilation, wherein the plasmid is stably maintained by the hostmicroorganism when cultured on glycerol as a carbon source. Such a plasmidmaintenance system is beneficial in applications where the presence of an antibioticresistance gene or the use of antibiotics is either prohibited or problem.

申请人:GLYCOS BIOTECHNOLOGIES, INC.

地址:Houston TX US

国籍:US

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