METHODS AND COMPOSITIONS FOR THE PREVENTION AND TR

专利名称：METHODS AND COMPOSITIONS FOR THE

PREVENTION AND TREATMENT OF DISEASE

发明人：D. Travis Wilson申请号：US15504944申请日：20150820

公开号：US20180193405A1公开日：20180712

摘要：The present technology is directed to compositions and methods forpreventing, ameliorating, or reducing the severity of one or more signs, or symptomsassociated with a reduction of function, decreased expression level of, and/or deficiencyin one or more of COL4A3, COL4A4 and COL4A5 genes. Also disclosed herein aremethods of preventing or treating Alport Syndrome in a mammalian subject, reducingrisk factors associated with Alport Syndrome, and/or reducing the likelihood or severityof Alport Syndrome. The methods comprise administering to the subject an effectiveamount of an aromatic-cationic peptide.

申请人：Stealth BioTherapeutics Corp

地址：Monaco MC

国籍：MC

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