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METHOD FOR DETERMINATION OF CELL VIABILITY BY USIN

来源:知库网
专利内容由知识产权出版社提供

专利名称:METHOD FOR DETERMINATION OF CELL

VIABILITY BY USING FLOW CYTOMETRYWITH FIXED VOLUME ACQUISITION

发明人:SCHINKÖTHE, Timo申请号:EP07857612.1申请日:20071214公开号:EP2095092A1公开日:20090902

摘要:The present invention provides a method for comparing the content of aspecific cell subpopulation in cell suspension samples by determining the count of cellsof said subpopulation per unit volume in each sample, using a flow cytometer with fixedvolume acquisition, but without the use of an internal or external standard. Thus, theeffect of a test compound on cell viability can be determined, especially the cytotoxic orcytostatic effect of anticancer drugs. The method is a useful tool for predicting thebiological activity of cytotoxic or cytostatic compounds on cells of the same kind as thecells in the sample. Furthermore, a kit for performing the method is provided.

申请人:TumorTec GmbH

地址:Eupener Str. 148 50933 Köln DE

国籍:DE

代理机构:Helbing, Jörg

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