Methods and Compositions for the Treatment of Eye

专利名称：Methods and Compositions for the

Treatment of Eye Disorders with IncreasedIntraocular Pressure

发明人：Ana I. Jimenez,Angela Sesto,Irene

Gascon,Jose P. Roman,Gonzalo Gonzalez deBuitrago

申请号：US12170078申请日：20080709

公开号：US20090099111A1公开日：20090416

专利附图：

摘要：The present invention relates to methods and compositions that decreaseintraocular pressure (IOP) of the eye. The compositions of the invention comprise shortinterfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decreaseexpression of genes associated with production or drainage of intraocular fluid. Thecompositions of the invention can be used in the preparation of a medicament for thetreatment of an eye conditions displaying increased IOP such as glaucoma, infection,inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprisethe administration to a patient in need thereof an effective amount of one or more siNAsof the invention.

申请人：Ana I. Jimenez,Angela Sesto,Irene Gascon,Jose P. Roman,Gonzalo Gonzalez deBuitrago

地址：Madrid ES,Madrid ES,Madrid ES,Vitoria ES,Madrid ES

国籍：ES,ES,ES,ES,ES

更多信息请下载全文后查看