专利名称：NUCLEIC ACID-BASED ASSEMBLY AND USE
THEREOF IN CANCER THERAPY
发明人：FAMULOK, Michael,PRUSTY,
Deepak,ADAM,Volker,IRSEN, Stephan
申请号：EP17829613.3申请日：20171207公开号：EP3551229A1公开日：20191016
摘要：The present invention relates to a nucleic acid-based assembly comprising: atleast one nucleic acid aptamer, and at least one nucleic acid motif designed to physicallycapture a drug, wherein the nucleic acid motif comprises one or more photo-responsivemoieties that effect the release of the drug upon irradiation, wherein the aptamer andthe nucleic acid motif each are covalently linked to one or more lipids, wherein the lipid-modified aptamer and nucleic acid motif form the assembly through noncovalentinteraction. The invention further relates to use of the nucleic acid-based assembly in thetreatment of cancer.
申请人：Rheinische Friedrich-Wilhelms-Universität Bonn,Stiftung Caesar
地址：Regina-Pacis-Weg 3 53113 Bonn DE,Ludwig-Erhard-Allee 2 53175 Bonn DE
国籍：DE,DE
代理机构：Patent Boutique LLP
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